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Related Experiment Video

Updated: Dec 9, 2025

Scratch Migration Assay and Dorsal Skinfold Chamber for In Vitro and In Vivo Analysis of Wound Healing
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A cat's scratch or a wolf's bite?

Haim Shmuely1,2, Gil Chernin2,3, Michael Giladi4

  • 1Department of Internal Medicine D, Kaplan Medical Centre, Rehovot, Israel.

Lupus
|September 9, 2020
PubMed
Summary

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This summary is machine-generated.

Bartonella henselae endocarditis can mimic systemic vasculitis. A patient with prosthetic valve endocarditis and positive anti-dsDNA antibodies was misdiagnosed with systemic lupus erythematosus (SLE).

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Rheumatology

Background:

  • Bartonella henselae endocarditis is a rare condition.
  • It can mimic systemic vasculitis, particularly in patients with valvulopathy.
  • Diagnosis can be challenging due to overlapping clinical features.

Observation:

  • A case of Bartonella henselae endocarditis involving a prosthetic pulmonic valve is presented.
  • The patient exhibited positive anti-dsDNA antibodies.
  • Initial diagnosis was systemic lupus erythematosus (SLE) based on revised classification criteria.

Findings:

  • Bartonella henselae infection can induce autoantibodies, including anti-dsDNA.
  • This can lead to misdiagnosis of autoimmune diseases like SLE.
Keywords:
Bartonella henselae endocarditisanti-dsDNAcongenital pulmonic stenosisfalse positivesystemic lupus erythematosus

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  • Prosthetic valve endocarditis requires specific diagnostic considerations.

    • Implications:

    • Clinicians should consider Bartonella henselae infection in patients with prosthetic valves and autoimmune markers.
    • Accurate diagnosis is crucial to avoid inappropriate immunosuppressive therapy for SLE.
    • This case highlights the importance of a broad differential diagnosis in infectious endocarditis.