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Updated: Dec 9, 2025
A Tuberculosis Molecular Bacterial Load Assay TB-MBLA
Published on: April 30, 2020
Effect of social development in reducing tuberculosis mortality In northeastern Brazil areas
Ana Angélica Rêgo Queiroz1, Thaís Zamboni Berra2, Alexandre Tadashi Inomata Bruce3
1Federal University of Rio Grande do Norte. Natal, Rio Grande do Norte, Brazil. aninha_arego@hotmail.com.
Introduction:
Tuberculosis (TB) is the primary cause of death among infectious diseases affecting groups in extreme poverty. Social improvements could reverse this situation in Brazil. This study aims to demonstrate the spatial relationship between social development (SD) and TB mortality in Natal, a city in northeastern Brazil.
Methodology:
Ecological study. The study population comprised TB deaths recorded in the Mortality Information System between 2008 and 2014. The units of analysis were 59 human development units (HDUs). Raw and smoothed mortality rates were calculated using the global empirical Bayes method. Primary components analysis was used to develop the SD indicators. An association between TB mortality and SD was verified using multiple linear regression analysis. Spatial autocorrelation was verified using models with global spatial effects. Analyses were performed using Statistica version 12.0, ArcGIS version 10.2, Statistical Package for the Social Sciences version 20.0, and OpenGeoDa 1.0.1. The significance level was established at 5% (p < 0.05).
Results:
The TB mortality rate with non-random spatial distribution ranged between 0.52 and 8.90 per 100,000 inhabitants. The spatial lag model was chosen because it presented the highest log-likelihood value, lowest AIC, and highest R2. A negative association was found between TB mortality and SD (R2 = 0.207; p = 0.03).
Conclusions:
The results show a negative association between TB mortality and the high SD indicator. This study can support decision-making in terms of collective projects within public health in order to link the health field to other sectors, aiming for social well-being and human development.
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