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Cathepsin B immunoreactivity is widely distributed in the rat brain
H G Bernstein1, H Kirschke, B Wiederanders
1Institute of Anatomy, Medical Academy Magdeburg, DDR.
Abstract:
The cellular localization and regional distribution of cathepsin B within rat CNS was revealed by immunohistochemistry using a monospecific antiserum. Cathepsin B protein was found to be widely but unevenly distributed throughout rat brain. Neurons were always cathepsin B immunoreactive. Glial elements were only occasionally immunostained. The distribution of the enzyme resembles largely that of cathepsin D.