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Related Experiment Video

Updated: Dec 9, 2025

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

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Higher Cortical Dysfunction Presenting as Visual Symptoms in Neurodegenerative Diseases.

Yin Liu^1,2, Victoria S Pelak³, Gregory van Stavern⁴

¹Department of Ophthalmology, Stanford University, Palo Alto, CA, United States.

Frontiers in Neurology

|September 9, 2020

Summary

Neuro-ophthalmologists evaluate visual symptoms in neurodegenerative diseases. Barriers like time, resources, and knowledge hinder diagnosis, necessitating further research for improved patient care.

Keywords:

Alzheimer's disease (AD)higher cortical dysfunction neurodegenerative diseases posterior cortical atrophy (PCA)visual symptoms

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Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

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Published on: December 8, 2023

Area of Science:

Neuroscience
Ophthalmology

Background:

Aging populations increase neurodegenerative disease prevalence, impacting healthcare.
Visual symptoms in neurodegenerative diseases are challenging to identify, especially with co-existing eye conditions.

Purpose of the Study:

To survey neuro-ophthalmologists on diagnosing visual dysfunction in neurodegenerative diseases.
To identify barriers encountered in diagnosing these visual complications.

Main Methods:

A seven-question web-based survey was administered to neuro-ophthalmologists at a 2017 symposium.
Survey content included demographics, patient prevalence, and perceived diagnostic barriers.

Main Results:

55 neuro-ophthalmologists participated; 40% attributed visual complaints to higher-order effects in at least 25% of patients with prior neurodegenerative disease diagnoses.
Key barriers included referral difficulties (73%), lack of time (62%), insufficient tools (40%), and limited knowledge (31%).

Conclusions:

Neuro-ophthalmologists diagnose visual symptoms in neurodegenerative diseases, but face significant barriers.
Lack of time, resources, and knowledge impede diagnosis, highlighting the need for improved diagnostic strategies and further research.