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The Role of Lower Extremity Amputation in Chronic Limb-Threatening Ischemia

Tanner I Kim1, Carlos Mena2, Bauer E Sumpio1,2

  • 1Division of Vascular Surgery, Department of Surgery, Yale University School of Medicine, New Haven, Connecticut.

The International Journal of Angiology : Official Publication of the International College of Angiology, Inc
|September 9, 2020
PubMed

Insights

Chronic limb-threatening ischemia (CLTI) management involves limb salvage through revascularization. For patients unsuitable for this, primary amputation is a crucial treatment option, improving outcomes in severe peripheral artery disease.

Area of Science:

  • Vascular Surgery
  • Peripheral Artery Disease Management

Background:

  • Chronic limb-threatening ischemia (CLTI) is a severe manifestation of peripheral artery disease.
  • CLTI carries a high risk of limb loss, necessitating effective treatment strategies.

Purpose of the Study:

  • To highlight the role of amputation in managing CLTI.
  • To identify patient selection criteria for primary amputation in CLTI.

Main Methods:

  • Review of treatment goals and outcomes in CLTI.
  • Discussion of patient suitability for revascularization versus amputation.

Main Results:

  • Multidisciplinary care improves limb salvage rates in CLTI.
  • A subset of CLTI patients requires major amputation.

Conclusions:

  • Amputation is a vital component in the CLTI management algorithm.
  • Primary amputation should be considered for specific CLTI patient profiles when revascularization is not feasible.

Keywords:
amputationarterychronic limb-threatening ischemiaend-stage renal diseaseperipheral artery diseaserisk factors

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