Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Environmental lead exposure and the kidney.

B P Bernard1, C E Becker

  • 1University of California, San Francisco.

Journal of Toxicology. Clinical Toxicology
|January 1, 1988
PubMed
Summary

Chronic low-level environmental lead exposure may subtly affect kidney function. This review critically examines the evidence linking lead exposure to renal function changes.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Repair of rotator cuff tears in golfers.

Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association·2001
Same author

Complications of blade plate removal.

Journal of pediatric orthopedics·1999
Same author

Modeling the acute neurotoxicity of styrene.

Journal of occupational and environmental medicine·1998
Same author

Evaluation of tremor in aluminum production workers.

Neurotoxicology and teratology·1997
Same author

Epidemiology of work-related musculoskeletal disorders.

The Orthopedic clinics of North America·1996
Same author

Treatment of pneumothorax in the patient with AIDS.

The Journal of the Kentucky Medical Association·1996

Area of Science:

  • Environmental Health
  • Toxicology
  • Nephrology

Background:

  • Lead is a ubiquitous environmental toxicant with no physiological role.
  • While acute lead poisoning is well-documented, subtle effects on organ systems are increasingly recognized.
  • Kidney function is a potential target for chronic, low-level lead exposure.

Purpose of the Study:

  • To review the historical association between lead exposure and kidney function.
  • To critically evaluate the current evidence linking low-level environmental lead exposure to renal effects.
  • To discuss the challenges in assessing lead body burden and subtle kidney function changes.

Main Methods:

  • Literature review of historical and recent studies on lead exposure and kidney function.
  • Critical analysis of epidemiological and toxicological data.
  • Examination of methodologies for assessing lead body burden and renal function.

Main Results:

  • Mounting evidence suggests chronic low-level lead exposure can subtly impair kidney function.
  • Traditional markers may not adequately detect early renal changes from lead.
  • Assessing lead's dose-response relationship on the kidneys remains challenging.

Conclusions:

  • Environmental lead exposure poses a subtle but significant risk to kidney health.
  • Further research is needed to refine methods for detecting and quantifying lead-induced renal damage.
  • Public health strategies should consider the impact of chronic low-level lead exposure on renal function.

Related Experiment Videos