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Updated: Dec 9, 2025

Retropinacol/Cross-pinacol Coupling Reactions - A Catalytic Access to 1,2-Unsymmetrical Diols
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Nickel-Catalyzed Enantioselective Reductive Cross-Coupling Reactions

Kelsey E Poremba1, Sara E Dibrell1, Sarah E Reisman1

  • 1The Warren and Katharine Schlinger Laboratory for Chemistry and Chemical Engineering, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.

ACS Catalysis
|September 9, 2020
PubMed
Summary

Nickel-catalyzed reductive cross-coupling reactions efficiently join electrophiles. Developing enantioselective variants for creating stereogenic centers is a key challenge in this field.

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