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Use of heated humidified high flow nasal cannula for obstructive sleep apnea in infants

Ka-Li Kwok1, Mei-Yee Lau1, Shuk-Yu Leung1

  • 1Department of Paediatrics, Kwong Wah Hospital, Hong Kong, China.

Sleep Medicine
|September 9, 2020
PubMed

Insights

Heated humidified high flow nasal cannula (HHHFNC) effectively treats obstructive sleep apnea (OSA) in infants. This non-invasive therapy significantly reduced respiratory events and improved oxygen saturation in infants with OSA.

Area of Science:

  • Pediatric Pulmonology
  • Sleep Medicine
  • Neonatology

Background:

  • Heated humidified high flow nasal cannula (HHHFNC) is increasingly used for pediatric respiratory distress.
  • Its application in infant obstructive sleep apnea (OSA) is not well-documented.
  • This study investigates HHHFNC as a treatment for OSA in infants.

Purpose of the Study:

  • To evaluate the efficacy of HHHFNC in treating infants diagnosed with obstructive sleep apnea.
  • To assess the impact of HHHFNC on respiratory events and oxygenation in this population.

Main Methods:

  • Retrospective analysis of infants with OSA undergoing polysomnographic titration between 2015 and 2017.
  • Data collected included age, gender, apnea-hypopnea index (AHI), comorbidities, and optimal HHHFNC flow rate.
  • Statistical analysis compared pre- and post-treatment respiratory parameters.

Main Results:

  • Ten infants (median age 34 weeks) were included.
  • Optimal HHHFNC flow rate was 8.0 L/min.
  • Significant reductions were observed in the obstructive apnea-hypopnea index (OAHI), obstructive apnea index (OAI), and obstructive hypopnea index (OHI).
  • Median oxygen saturation (SpO2) nadir significantly increased from 88% to 94% (P=0.040).

Conclusions:

  • HHHFNC therapy is effective in reducing respiratory events in infants with OSA.
  • HHHFNC significantly improves oxygenation in infants suffering from obstructive sleep apnea.
  • This non-invasive approach shows promise for managing infant OSA.
Abstract

Keywords:
Heated humidified high-flow nasal cannulaInfantObstructive sleep apnea

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