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Updated: Dec 9, 2025

Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering
Published on: March 1, 2016
pH-Responsive polymers: synthesis, properties and applications
Sheng Dai1, Palaniswamy Ravi2, Kam Chiu Tam3
1National Institute for Nanotechnology, National Research Council Canada, 11421 Saskatchewan Drive, Edmonton, Alberta T6G 2M9, Canada.
Abstract:
pH-Responsive polymers are systems whose solubility, volume, and chain conformation can be manipulated by changes in pH, co-solvent, and electrolytes. This review summarizes recent developments covering synthesis, physicochemical properties, and applications in various disciplines. A variety of synthetic methodologies comprising of emulsion polymerization and living radical polymerization techniques are described, and some of their salient features are highlighted. Several polymeric systems, such as homopolymers, block copolymers, microgels, hydrogels and polymer brushes at interfaces are reviewed, where important characteristics that govern their behavior in solutions are described. Potential applications of these systems in controlled drug delivery, personal and home care, industrial coatings, biological and membrane science, viscosity modifiers, colloid stabilization, and water remediation, are discussed.
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