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Updated: Dec 9, 2025

Multiplexing Focused Ultrasound Stimulation with Fluorescence Microscopy
Published on: January 7, 2019
Lag-Based Filtered-Delay Multiply and Sum Beamformer Combined with Two Phase-Related Factors for Medical Ultrasound
Ke Song1, Paul Liu2, Dong C Liu3
1School of Mathematics and Information Engineering, Chongqing University of Education, Chongqing 400065, China.
Abstract:
A novel adaptive beamformer named filtered-delay multiply and sum (F-DMAS) has recently been proposed. Compared to the delay and sum (DAS) beamforming algorithm, F-DMAS can efficiently improve the resolution and contrast. However, the DAS can still be seen in the expansion of DMAS. Therefore, we rearrange the pair-wised signals in terms of lag in DMAS and then synthesize a lot of new signals. Thanks to the relationship between the spatial coherence and lag, these new signals can be thought of as sorted by the spatial coherence. Thus, we apply two phase-related factors, the polarity-based factor (PF) and the sign coherence factor (SCF), which are evaluated based on new signals, to weight the output of DMAS. The two approaches are consequently referred to as LAG-DMAS-PF and LAG-DMAS-SCF, respectively. The results show that, compared to F-DMAS and DAS, our proposed methods can improve the resolution and contrast to some extent without increasing too much computational complexity. In the comparison between LAG-DMAS-PF and LAG-DMAS-SCF, the latter has better performance, but the former can better protect image details.
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