Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pituitary gland.

E Horvath1, K Kovacs

  • 1Department of Pathology, St. Michael's Hospital University of Toronto, Ontario, Canada.

Pathology, Research and Practice
|April 1, 1988
PubMed
Summary
This summary is machine-generated.

This review covers human pituitary proliferative lesions, focusing on established adenoma classification and the emerging understanding of pituitary hyperplasia. Further research is needed to fully define hyperplasia and uncover new pituitary cell types.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Expression of hypoxia-inducible factor-1alpha (HIF-1alpha) in pituitary tumours.

Histology and histopathology·2003
Same author

Increased nuchal translucency and decreased fetomaternal transfusion after chorionic villus sampling.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2003
Same author

Additive neuroprotective effect of Ketanserin and Ipsapirone on the hippocampal damage after transient forebrain ischemia in the Mongolian gerbil.

Neuroscience letters·2003
Same author

Pituitary adenoma in Carney complex: an immunohistochemical, ultrastructural, and immunoelectron microscopic study.

Ultrastructural pathology·2003
Same author

Composite somatotroph--ACTH-immunoreactive pituitary adenoma with transformation of hyperplasia to adenoma.

Pituitary·2002
Same author

Pulse and continuous oral norfloxacin treatment of experimentally induced Escherichia coli infection in broiler chicks and turkey poults.

Acta veterinaria Hungarica·2002
Same journal

A novel oxygen-releasing bilayer delivery system for cell survival and peripheral nerve regeneration.

Pathology, research and practice·2026
Same journal

Autophagy modulation in ulcerative colitis with traditional Chinese medicine: A review.

Pathology, research and practice·2026
Same journal

Ras signalling in infectious disease pathology: Mechanisms, tissue damage, and clinical implications.

Pathology, research and practice·2026
Same journal

CBFβ-SMMHC in inv(16) AML: Fusion biology, RUNX1 dysregulation, and therapeutic targeting of a leukemogenic protein-protein interaction.

Pathology, research and practice·2026
Same journal

Multifactorial pathophysiology of varicocele: Integrating hemodynamic, oxidative, and endocrine mechanisms.

Pathology, research and practice·2026
Same journal

Comparative pathophysiology and pathology of transient ischemic attack, ischemic stroke, and reperfusion injury: Mechanistic and therapeutic perspectives.

Pathology, research and practice·2026
See all related articles

Area of Science:

  • Endocrinology
  • Pathology
  • Cell Biology

Background:

  • The morphologic classification of pituitary adenomas is well-established, utilizing histology, immunohistochemistry, and electron microscopy.
  • All known adenohypophysial cell types can form adenomas, potentially leading to excess pituitary hormone secretion.
  • Pituitary hyperplasia is increasingly recognized as a cause of hypersecretory syndromes, mirroring adenoma-related conditions.

Purpose of the Study:

  • To review current knowledge on the pathology of proliferative lesions in the human pituitary.
  • To discuss the diagnostic challenges associated with pituitary hyperplasia.
  • To highlight unresolved issues in pituitary pathology, including structure-function relationships and lesion pathogenesis.

Main Methods:

Related Experiment Videos

  • Histology
  • Immunohistochemistry
  • Electron microscopy
  • Literature review

    • Main Results:

    • Established morphologic classification for pituitary adenomas.
    • Evidence suggests pituitary hyperplasia can mimic adenoma-induced hypersecretory syndromes.
    • Pituitary hyperplasia remains incompletely defined due to limited studies and diagnostic difficulties.

    Conclusions:

    • Despite advances, the pathogenesis and structure-function relationships of pituitary proliferative lesions require further investigation.
    • The current cytological mapping of the pituitary may be incomplete, with potential for undiscovered cell types.
    • Further research is essential for a comprehensive understanding of pituitary hyperplasia and adenoma development.