[Living related liver transplantation]

Area of Science:

• Transplantation Surgery
• Hepatology
• Organ Donation

Background:

• Liver transplantation is a standard treatment for end-stage liver disease.
• A shortage of suitable donor organs limits liver transplantation procedures.
• Utilizing marginal organs and living liver donation can address organ scarcity.

Purpose of the Study:

• To explore the potential of living liver donation as a solution to organ shortages.
• To compare the outcomes of liver transplantation from living versus deceased donors.
• To highlight the technical aspects and donor evaluation in partial liver donation.

Main Methods:

• Review of current practices in liver transplantation and organ donation.
• Analysis of techniques for utilizing marginal organs, including machine perfusion.
• Description of the process and outcomes of living donor liver transplantation.
• Comparison with split liver transplantation from post-mortem donors.

Main Results:

• Living liver donation is a viable option to overcome donor organ limitations.
• Partial liver donation techniques are adapted from oncological liver resections.
• Specialized centers report comparable or superior results with living donor liver transplantation.
• Donor evaluation protocols aim to minimize risks associated with living donation.

Conclusions:

• Living liver donation is a critical strategy to expand the donor pool for liver transplantation.
• The outcomes of living donor liver transplantation are increasingly competitive with deceased donor transplants.
• Careful donor selection and surgical expertise are paramount for successful living liver donation.