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Related Experiment Video

Updated: Dec 9, 2025

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
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Skin Microbiome as Years Go By.

Paula Carolina Luna1

  • 1Hopital Alemán, Pueyrredón Av 1640, C1118 AAT, Buenos Aires, Argentina. dermatopaulaluna@gmail.com.

American Journal of Clinical Dermatology
|September 10, 2020
PubMed
Summary

The skin microbiome changes throughout life, impacting skin health and disease. Understanding these dynamic microbial communities is key for targeted treatments and monitoring vulnerable populations.

Area of Science:

  • Microbiology
  • Dermatology
  • Human Microbiome Research

Background:

  • The skin microbiota is crucial for maintaining skin barrier function and adapts to environmental changes across the lifespan.
  • Understanding the dynamic nature of the skin microbiome is essential for comprehending skin physiology and disease.

Purpose of the Study:

  • To review major alterations in the skin microbiome throughout human life, from infancy to old age.
  • To identify factors influencing skin microbiome composition and function at different life stages.
  • To discuss the link between skin microbiome dysbiosis and skin diseases.

Main Methods:

  • Literature review of studies on skin microbiome development and changes across the human lifespan.
  • Analysis of factors affecting skin microbiome structure, function, and composition.

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  • Discussion of the implications of microbiome alterations for skin health and disease pathophysiology.

    • Main Results:

    • The skin microbiome is established early in life and undergoes significant changes throughout different life stages.
    • Various factors influence the skin microbiome's composition and function, with alterations potentially leading to skin conditions.
    • Age-related changes in the skin microbiome are observed from infancy through older populations.

    Conclusions:

    • A comprehensive understanding of the skin microbiome across all age groups is vital for insights into skin disease mechanisms.
    • Targeted monitoring and treatment strategies for vulnerable populations can be improved by studying the skin microbiome.
    • Further research into the skin microbiome's role in health and disease is warranted for advancing dermatological care.