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A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
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COVID-19 and Sodium-Glucose Cotransporter 2 Inhibitors: No Fear to Attempt?

Stella Papachristou1, Theano Penlioglou1, Anca Pantea Stoian2

  • 1Diabetes Centre, Second Department of Internal Medicine, Democritus University of Thrace, Alexandroupolis, Greece.

Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [And] German Diabetes Association
|September 10, 2020
PubMed

Insights

The COVID-19 pandemic disproportionately affects older adults and individuals with diabetes mellitus (DM). Many COVID-19 fatalities, particularly in Italy, were linked to pre-existing DM.

Area of Science:

  • Epidemiology
  • Infectious Diseases
  • Public Health

Background:

  • The COVID-19 pandemic, declared by the WHO, presents a significant global health challenge.
  • Increased mortality and morbidity rates are observed in elderly populations and individuals with comorbidities.
  • Diabetes mellitus (DM) is a prevalent comorbidity associated with severe COVID-19 outcomes.

Purpose of the Study:

  • To highlight the heightened risk of severe outcomes and mortality in elderly individuals with COVID-19.
  • To emphasize the significant role of diabetes mellitus (DM) as a comorbidity in COVID-19.
  • To present data on the prevalence of DM among COVID-19 fatalities.

Main Methods:

  • Literature review and data synthesis on COVID-19 impact.
  • Analysis of mortality data stratified by age and comorbidities.
  • Epidemiological surveillance data interpretation.

Main Results:

  • COVID-19 mortality and morbidity are significantly higher in the elderly.
  • Individuals with comorbidities like DM face elevated risks.
  • In Italy, two-thirds of COVID-19 deaths were among individuals with DM.

Conclusions:

  • Elderly individuals and those with DM are a vulnerable population during the COVID-19 pandemic.
  • Diabetes mellitus is a critical factor contributing to COVID-19 severity and mortality.
  • Public health strategies must prioritize these high-risk groups.

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