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Paracoccidioidomycosis: an uncommon clinical presentation
Bruno Augusto Alvares1, Cláudia Alves Lapa Gracia2, Mariangela Esther Alencar Marques1
1Department of Dermatology and Radiotherapy, Faculdade de Medicina, Universidade Estadual Paulista, Botucatu, SP, Brazil.
Paracoccidioidomycosis, a fungal infection, typically affects rural males. This case highlights an atypical presentation in an elderly urban female, successfully treated with itraconazole.
Area of Science:
- Medical Mycology
- Infectious Diseases
Background:
- Paracoccidioidomycosis (PMSC) is a systemic fungal infection endemic to Latin America.
- It predominantly affects adult males with occupational or environmental exposure to rural areas.
- The classic presentation involves oro-pulmonary lesions.
Observation:
- A 76-year-old female patient with no history of rural exposure presented with an atypical clinical-dermatological manifestation of PMSC.
- Diagnosis was confirmed via histopathological examination.
Findings:
- The patient exhibited an unusual clinical presentation of paracoccidioidomycosis.
- Histopathology was crucial for accurate diagnosis.
Implications:
- This case expands the known clinical spectrum of paracoccidioidomycosis.
- It underscores the importance of considering atypical presentations in diverse patient demographics.
- Successful treatment with itraconazole demonstrates its efficacy in managing this rare presentation.
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