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Related Experiment Video

Updated: Dec 9, 2025

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Fetal Exposure to MR Imaging: Long-Term Neurodevelopmental Outcome.

E Zvi1,2, A Shemer2, S Toussia-Cohen3,2

  • 1From the Antenatal Diagnostic Unit (E.Z., S.t.-C., O.E., E.K.) elad.zvi@gmail.com.

AJNR. American Journal of Neuroradiology
|September 11, 2020
PubMed
Summary

Prenatal exposure to 1.5T noncontrast MR imaging shows no adverse long-term neurodevelopmental effects in children. This finding supports the safety of maternal magnetic resonance imaging (MRI) use during pregnancy.

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Area of Science:

  • Neuroscience
  • Radiology
  • Pediatrics

Background:

  • Limited research exists on the long-term neurodevelopmental effects of prenatal exposure to magnetic resonance (MR) imaging.
  • Assessing these effects is crucial for understanding the safety of MR imaging during pregnancy.

Purpose of the Study:

  • To evaluate the long-term neurodevelopmental outcomes in children exposed to MR imaging antenatally.
  • To compare neurodevelopmental assessments between children with and without prenatal MR imaging exposure.

Main Methods:

  • A historical prospective cohort study was conducted.
  • Women undergoing 1.5T noncontrast MR imaging for maternal or fetal reasons were matched with unexposed controls.
  • Children's neurodevelopment was assessed using the Vineland-II Adaptive Behavior Scale between 2.5 and 6 years of age.

Main Results:

  • No significant differences were found in the overall composite scores of the Vineland-II Adaptive Behavior Scale between exposed and unexposed children.
  • Specific domains including communication, daily living skills, and motor skills showed no significant differences between the groups.
  • A statistically significant favorable difference was observed in the socialization domain for children exposed to MR imaging prenatally.

Conclusions:

  • Prenatal exposure to 1.5T noncontrast MR imaging does not appear to have harmful effects on long-term neurodevelopment.
  • The findings contribute to the body of evidence supporting the safety of utilizing MR imaging during pregnancy.