Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Treatment Resistant Cancers02:56

Treatment Resistant Cancers

3.6K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.6K
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

5.7K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
5.7K
Tumor Immunotherapy01:27

Tumor Immunotherapy

1.4K
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
1.4K
Cancer Therapies02:49

Cancer Therapies

9.7K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
9.7K
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

8.5K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
8.5K
Genomics02:02

Genomics

39.2K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
39.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Stereo-electroencephalography-guided cross-electrode radiofrequency thermocoagulation in focal epilepsy: A review of current methodologies and outcomes.

Epilepsia·2026
Same author

A Framework for MRI Characterization of Intracranial Metastatic Disease.

Radiology. Imaging cancer·2026
Same author

Timing for Starting Antiseizure Medication Withdrawal After Epilepsy Surgery in Adults.

Neurology·2026
Same author

The role of neuroimaging in neurotoxicity after chimeric antigen receptor T-cell therapy.

Therapeutic advances in neurological disorders·2026
Same author

Patient-derived organoids and neurospheres recapitulate salient features of primary tumor heterogeneity.

Neuro-oncology advances·2026
Same author

Increased neural excitability and glioma synaptic activity drives glioma proliferation in human cortex.

Nature neuroscience·2025
Same journal

Multiparametric MRI Model Predicts Parenchymal Hematoma in Acute Ischemic Stroke After Reperfusion.

AJNR. American journal of neuroradiology·2026
Same journal

Age- and Region-Stratified Growth in Emergency Department Neuroimaging Utilization within Epic Cosmos, 2016-2025.

AJNR. American journal of neuroradiology·2026
Same journal

Neuroradiology Leads NIH Funding Among Clinician Diagnostic Radiologists: A 14-Year National Analysis.

AJNR. American journal of neuroradiology·2026
Same journal

Neutral Cervical Spine MRI is Not Enough: The Critical Role of Flexion Imaging in Hirayama disease in Pediatric Patients.

AJNR. American journal of neuroradiology·2026
Same journal

CT Evaluation of Osseous Trauma at the Craniocervical Junction: A Pattern-Based Overview.

AJNR. American journal of neuroradiology·2026
Same journal

Comprehensive Structural MRI Phenotyping in <i>Oligophrenin 1-</i>Related Disorder Reveals Characteristic Brain Malformations.

AJNR. American journal of neuroradiology·2026
See all related articles

Related Experiment Video

Updated: Dec 9, 2025

Quantifying the Brain Metastatic Tumor Micro-Environment using an Organ-On-A Chip 3D Model, Machine Learning, and Confocal Tomography
09:53

Quantifying the Brain Metastatic Tumor Micro-Environment using an Organ-On-A Chip 3D Model, Machine Learning, and Confocal Tomography

Published on: August 16, 2020

7.5K

Neuro-Oncology and Radiogenomics: Time to Integrate?

A Lasocki1,2, M A Rosenthal3, S J Roberts-Thomson4

  • 1From the Department of Cancer Imaging (A.L.) arian.lasocki@petermac.org.

AJNR. American Journal of Neuroradiology
|September 11, 2020
PubMed
Summary
This summary is machine-generated.

Radiogenomics can help manage intracranial gliomas by predicting genetic markers from imaging. This review explores clinical uses to bridge the gap between research and patient care.

More Related Videos

Combination Radiotherapy in an Orthotopic Mouse Brain Tumor Model
08:02

Combination Radiotherapy in an Orthotopic Mouse Brain Tumor Model

Published on: March 6, 2012

16.8K
Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology
07:03

Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology

Published on: December 1, 2023

1.3K

Related Experiment Videos

Last Updated: Dec 9, 2025

Quantifying the Brain Metastatic Tumor Micro-Environment using an Organ-On-A Chip 3D Model, Machine Learning, and Confocal Tomography
09:53

Quantifying the Brain Metastatic Tumor Micro-Environment using an Organ-On-A Chip 3D Model, Machine Learning, and Confocal Tomography

Published on: August 16, 2020

7.5K
Combination Radiotherapy in an Orthotopic Mouse Brain Tumor Model
08:02

Combination Radiotherapy in an Orthotopic Mouse Brain Tumor Model

Published on: March 6, 2012

16.8K
Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology
07:03

Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology

Published on: December 1, 2023

1.3K

Area of Science:

  • Neuroimaging
  • Oncology
  • Genetics

Background:

  • Radiogenomics links imaging features to genetic markers, crucial for intracranial glioma diagnosis and management.
  • Despite research growth, clinical translation of radiogenomics remains limited, creating a gap between advanced techniques and patient care.
  • The fundamental goal of radiogenomics is to enhance patient care through improved diagnostic and management strategies.

Purpose of the Study:

  • To review clinical scenarios where radiogenomics can aid intracranial glioma patient management.
  • To explore how radiogenomics can facilitate patient counseling and inform treatment decisions.
  • To discuss overcoming limitations in histologic assessment and reclassifying tumors using radiogenomics.

Main Methods:

  • Literature review of radiogenomics applications in neuro-oncology.
  • Analysis of potential clinical integration points for radiogenomic data.
  • Discussion of feature selection strategies for clinical radiogenomics.

Main Results:

  • Radiogenomics can support patient counseling by providing predictive genetic information.
  • It offers solutions for treatment planning when molecular characterization is incomplete.
  • Radiogenomics can refine tumor classification and mitigate limitations of traditional histology.

Conclusions:

  • Radiogenomics holds significant potential to improve clinical management of intracranial gliomas.
  • Bridging the gap between research and practice requires focusing on practical clinical applications.
  • Strategic implementation of radiogenomics can enhance precision in neuro-oncology.