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Efficient Recombinant Parvovirus Production with the Help of Adenovirus-derived Systems
Published on: April 23, 2012
[Development of mucoviscidosis management in East Germany]
1Klinik für Kinderheilkunde der Medizinischen Akademie Carl Gustav Carus, Dresden, DDR.
Abstract:
The development of cystic fibrosis care in the GDR is reported by the activities of the "Working Group for Combatting Cystic Fibrosis" in the Pediatric Association of the GDR during the last 20 years. The mean incidence of the disease amounts to 1:4,100. It could be demonstrated that both the number of patients and their mean life expectancy have been increased continuously. At the end of 1985 803 patients were under care in the GDR, 10.6 per cent of them have reached the age of 18 years or more. New problems in medical care and psychological guidance arise in adolescents and in young adults with cystic fibrosis. By using linkage analysis of genetic markers new possibilities have been revealed in the field of prenatal diagnosis and of heterozygote detection.
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