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Published on: July 5, 2021
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Olfactory outcomes after endonasal skull base surgery: a systematic review
Junhao Zhu1,2, Kaiyang Feng3, Chao Tang2
1Jinling Hospital, School of Medicine, Nanjing Medical University, 104 Hanzhong Road, Nanjing, 210002, China.
Neurosurgical Review
|September 11, 2020
Summary
Endoscopic endonasal surgery improves olfactory outcomes compared to microscopic approaches for skull base lesions. Avoiding septal flaps and considering rescue flap techniques enhance olfactory recovery.
Area of Science:
- Neurosurgery
- Otolaryngology
- Skull Base Surgery
Background:
- Endonasal surgery is common for skull base lesions.
- Postoperative olfactory dysfunction is a persistent challenge.
Purpose of the Study:
- Identify factors influencing olfactory prognosis after endonasal surgery.
- Compare olfactory outcomes between endoscopic and microscopic techniques.
Main Methods:
- Systematic review of 19 articles.
- Included studies with objective olfactory assessments.
- Meta-analysis of olfactory function rates.
Main Results:
- Endoscopic surgery showed better olfactory prognosis (18.48%) vs. microscopic (36.88%).
- Septal flap harvesting negatively impacted olfactory recovery.
- Middle turbinate resection did not show detrimental effects on olfaction.
Conclusions:
- Endoscopic endonasal surgery offers superior olfactory outcomes for sellar/parasellar lesions.
- Prioritize rescue flap techniques over septal flaps for better olfactory recovery.
- Middle turbinate resection appears safe for olfaction.
