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[Congenital type I diabetes]
1Abteilung Neonatologie Frauenklinik, im Krankenhaus, Berlin-Kaulsdorf.
Insights
Congenital type 1 diabetes, a rare condition, was identified in one infant born to a diabetic mother. This case highlights the importance of monitoring infants of diabetic mothers for early signs of insulin-dependent diabetes.
Area of Science:
- Endocrinology
- Pediatrics
- Genetics
Background:
- Maternal diabetes poses risks to offspring, including metabolic complications.
- Congenital or neonatal diabetes is a rare but serious condition requiring immediate intervention.
- Understanding the etiology of early-onset diabetes is crucial for management and prevention.
Abstract:
This is a case report about a connatal type I diabetes in a offspring of a diabetic mother. In series of 904 deliveries of diabetic women we found one case of connatal insulin-dependent diabetes. Insulin treatment has been necessary from the 7th day of life on. The need of insulin was up to 17 IE/d (mean blood glucose values between 5.5 and 6 mmol/l, acetone was negative). Genetic and immunologic reasons have been discussed.