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Updated: Dec 9, 2025

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Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
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What Are the Odds of Finding a COVID-19 Drug from a Lab Repurposing Screen?
1Structural Genomics Consortium, University of Toronto, 101 College Street, Seventh Floor, South Tower, Toronto, Canada M5G 1L6.
Journal of Chemical Information and Modeling
|September 11, 2020
Abstract:
Massive drug repurposing (or repositioning) campaigns are trying to find potential antiviral treatments for COVID-19. Many involve experimental or virtual screening of libraries of compounds previously proven safe in humans-"old drugs". In 20 years of these efforts in many other diseases, never has a new therapeutic hypothesis derived from screening of old drugs in a lab led to the drug being approved for the new indication.

