Platinum and zinc oxide modified carbon nitride electrode as non-enzymatic highly selective and reusable...

Development of non-enzymatic glucose sensor is essential to reduce the cost of diabetes regular monitoring. Here, graphitic carbon nitride (g-C₃N₄) is modified with platinum and zinc oxide for non-enzymatic electrochemical glucose sensing in physiological conditions for the first time in the literature. The interactions between Pt, g-C₃N₄ and the ZnO are studied using different physicochemical characterization techniques. The Electrochemical glucose sensing at the ZnO-Pt-gC₃N₄ occurs at low applied potential of +0.20 V (vs. Ag/AgCl) with high sensitivity 3.34 μA/mM/cm² and fast response (5 s) time. This sensor exhibited a wide linear range 0.25-110 mM with lower limit of detection of 0.1 µM. The architectured sensor was evaluated in human blood, serum and urine samples. The sensor is 4 time reusable in whole blood without activity deterioration. This reusable surface helps to reduce the cost of strip.