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Materials Testing for the Development of Biocompatible Devices through Vat-Polymerization 3D Printing
Gustavo González1,2, Désirée Baruffaldi1,3, Cinzia Martinengo1,3
1Dipartimento di Scienza Applicata e Tecnologia, Politecnico di Torino, C.so Duca degli Abruzzi 24, 10129 Turin, Italy.
Nanomaterials (Basel, Switzerland)
|September 12, 2020
Summary
Digital Light Processing (DLP) 3D printing can create custom biomedical devices. Optimizing resin formulations and post-printing treatments is crucial for ensuring the biocompatibility of these 3D printed parts for biological applications.
Area of Science:
- Biomedical Engineering
- Materials Science
- Additive Manufacturing
Background:
- Light-based 3D printing offers high precision and material flexibility for biomedical devices.
- Further research into the biocompatibility of 3D printed materials is needed for healthcare applications.
Purpose of the Study:
- To assess the biocompatibility of 3D printed polymeric parts using Digital Light Processing (DLP) technology.
- To compare different resin formulations and optimize post-printing protocols for biocompatible device fabrication.
Main Methods:
- Fabrication of 3D printed parts using a commercial DLP printer with various resin formulations.
- Investigation of biocompatibility using the A549 cell line.
- Optimization of post-printing procedures, including solvent washing and UV post-curing.
Main Results:
- Successfully fabricated 3D printed components suitable for biological studies.
- Identified that both material selection and post-printing protocols are critical for achieving biocompatibility.
- Demonstrated the removal of unreacted and cytotoxic products through optimized protocols.
Conclusions:
- Digital Light Processing (DLP) 3D printing is a viable technique for producing biocompatible components for biomedical applications.
- Comprehensive post-printing treatments are essential to ensure the safety and efficacy of 3D printed medical devices.
