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Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
07:41

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure

Published on: February 8, 2022

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Early changes in ambulatory electrocardiography after transcatheter closure in patients with atrial septal defect and

Zhenyang Su1, Qing Cao1, Hao Zhang2

  • 1Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, No. 300, Guangzhou Road, Nanjing, 210029, China.

BMC Cardiovascular Disorders
|September 12, 2020
PubMed

Insights

Heart rate variability (HRV) improved after atrial septal defect (ASD) closure. Key factors influencing HRV in ASD patients include age, sex, heart rate, defect size, and diabetes, with right ventricular systolic pressure also playing a role.

Area of Science:

  • Cardiology
  • Medical Devices
  • Clinical Research

Background:

  • Heart rate variability (HRV) factors in atrial septal defect (ASD) patients remain unclear.
  • Understanding these factors is crucial for patient management and risk stratification.

Purpose of the Study:

  • To identify factors influencing HRV in ASD patients.
  • To develop a preliminary risk model for HRV changes in ASD.

Main Methods:

  • Analysis of 154 ASD patients undergoing transcatheter closure and 26 patent foramen ovale (PFO) controls.
  • Echocardiography and ambulatory electrocardiography performed pre- and post-procedure.

Main Results:

  • Significant improvements in HRV indices (SDNN, SDANN) and a decrease in heart rate were observed post-ASD closure.
  • Multiple regression identified age, sex, defect diameter, heart rate, and diabetes as significant predictors of HRV.
  • Right ventricular systolic pressure showed a significant correlation with HRV indices.

Conclusions:

  • Age, sex, heart rate, defect size, and diabetes are key determinants of HRV in ASD patients.
  • Right ventricular systolic pressure is an important factor influencing HRV changes in this population.
Abstract

Keywords:
Ambulatory electrocardiographyAtrial septal defectHeart rate variabilityTranscatheter closure

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