Related Experiment Video
Updated: Dec 9, 2025
An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
Published on: October 10, 2025
Ganglioneurofibroma arising within the extralobar pulmonary sequestration
Yuanyuan Liu1, Wenbin Wu2, Longbo Gong2
1Department of Respiratory and Critical Care Medicine, Xuzhou Central Hospital, Xuzhou, China.
Background:
Neurogenic tumor arising within the pulmonary sequestration (PS) is rare.
Case Presentation:
A 42-year-old asymptomatic female was referred to our hospital for work-up of extralobar PS. The independent feeding artery from the thoracic aorta was confirmed by three-dimensional computed tomography angiography (3D-CTA). Uniportal thoracoscopic resection of the sequestrated lung with mediastinal lymph node sampling was performed successfully. Ganglioneurofibroma within the PS was diagnosed as the specimen revealed positive expression of SRY-related HMG-box 10 protein, neuron-specific enolase, S-100, chromogranin A and synuclein. Tumor recurrence was not recorded 1 year after the surgery.
Conclusion:
Preoperative 3D-CTA is useful to identify the aberrant vessels of PS. An elaborate diagnostic work-up after a timely resection is necessary for subsequent management and follow-up plan.
