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Updated: Dec 9, 2025
Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
Efficacy of argon-helium cryoablation and its effects on immune function of patients with neck malignant tumours
Zheng Zheng1, Yingchun Zhao1, Yonghui An1
1Department of Oncology, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Objectives:
Our study aimed to investigate the clinical efficacy of argon-helium cryoablation and its effects on the immune function of patients with neck malignant tumours.
Design:
Retrospective study.
Setting:
Single-institution academic tertiary care centre.
Methods:
Totally, 180 patients harbouring head and neck malignant tumours were divided into the argon-helium cryoablation group (n = 150) and the radiotherapy group (n = 50). The efficacy of the two groups was compared, and the immune function was observed.
Results:
The short-term clinical effect of the argon-helium cryoablation group was significantly higher than that of the radiotherapy group (P < .05). After treatment, the CD3+, CD4+, CD8+ and CD4+/CD8+ of the argon-helium cryoablation group were significantly better than those of the radiotherapy group (P < .001). The results of TNF-α, IL-1 β and CRP in the argon-helium cryoablation group were significantly better than that in the radiotherapy group (P < .001).
Conclusion:
Argon-helium cryoablation could effectively improve the immune function, 5-year survival rate and local remission rate.
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