Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recent advances in 1,3,5-triazine-based PI3K inhibitors for cancer therapy: a comprehensive review.

Future medicinal chemistry·2026
Same author

Atypical Presentation of Classical Hodgkin Lymphoma as Superior Vena Cava Syndrome With Paraneoplastic Eosinophilia and Rash: A Case Report.

Cureus·2026
Same author

Effect of non-consecutive treatment during hypofractionated stereotactic radiosurgery (HF-SRS) for brain metastases.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2026
Same author

Percutaneous balloon compression followed by perineural methylprednisolone for trigeminal neuralgia: A 50-patient retrospective series with 12-month outcomes.

Clinical neurology and neurosurgery·2026
Same author

Revisiting the SURPLUS Procedure-A Hybrid Solution to the Complex Aortic Root.

Annals of thoracic surgery short reports·2026
Same author

The changing spectrum of neurointensive care unit needs for tumor patients.

Neuro-oncology advances·2026

Related Experiment Video

Updated: Dec 9, 2025

Thermal Ablation for the Treatment of Abdominal Tumors
07:16

Thermal Ablation for the Treatment of Abdominal Tumors

Published on: March 7, 2011

34.9K

Laser Ablation for Cerebral Metastases.

Evan Luther1, Samuel Mansour2, Nikolas Echeverry2

  • 1Department of Neurosurgery, University of Miami Miller School of Medicine, Miami, FL, USA; Department of Neurological Surgery, University of Miami/Jackson Health System, Lois Pope Life Center, 2nd Floor, 1095 Northwest 14th Terrace, Miami, FL 33136, USA.

Neurosurgery Clinics of North America
|September 14, 2020
PubMed
Summary

Laser interstitial thermal therapy (LITT) offers a minimally invasive surgical option for brain tumors, comparable to traditional craniotomy. This technique shows promise for recurrent brain metastases, warranting further research as a primary treatment.

Keywords:
Brain metastasisBrain tumorLaser ablationLaser interstitial thermal therapyMetastasesMinimally invasive surgeryNeuro-oncologyOncology

More Related Videos

An Immunocompetent Murine Model for Laser Interstitial Thermal Therapy of Glioblastoma
09:10

An Immunocompetent Murine Model for Laser Interstitial Thermal Therapy of Glioblastoma

Published on: November 15, 2024

713
Application of Laparoscopic Hepatectomy Combined with Intraoperative Microwave Ablation in Colorectal Cancer Liver Metastasis
04:22

Application of Laparoscopic Hepatectomy Combined with Intraoperative Microwave Ablation in Colorectal Cancer Liver Metastasis

Published on: March 3, 2023

727

Related Experiment Videos

Last Updated: Dec 9, 2025

Thermal Ablation for the Treatment of Abdominal Tumors
07:16

Thermal Ablation for the Treatment of Abdominal Tumors

Published on: March 7, 2011

34.9K
An Immunocompetent Murine Model for Laser Interstitial Thermal Therapy of Glioblastoma
09:10

An Immunocompetent Murine Model for Laser Interstitial Thermal Therapy of Glioblastoma

Published on: November 15, 2024

713
Application of Laparoscopic Hepatectomy Combined with Intraoperative Microwave Ablation in Colorectal Cancer Liver Metastasis
04:22

Application of Laparoscopic Hepatectomy Combined with Intraoperative Microwave Ablation in Colorectal Cancer Liver Metastasis

Published on: March 3, 2023

727

Area of Science:

  • Neurosurgery
  • Oncology
  • Minimally Invasive Procedures

Background:

  • Craniotomy is a traditional surgical approach for brain lesions.
  • High-risk patients often face significant morbidity with craniotomy.
  • Laser interstitial thermal therapy (LITT) presents a less invasive alternative.

Purpose of the Study:

  • To evaluate the efficacy and safety of LITT in neuro-oncology.
  • To compare LITT outcomes with craniotomy and radiation therapy.
  • To assess LITT's potential for treating recurrent brain metastases.

Main Methods:

  • Utilizing laser light via a fiber optic probe inserted into the target lesion.
  • Inducing controlled thermal tissue damage to achieve cellular death.
  • Employing LITT as a minimally invasive surgical technique.

Main Results:

  • LITT complication rates and outcomes are comparable to craniotomy and radiation.
  • LITT is an effective option for managing recurrent brain metastases.
  • The procedure facilitates treatment of inaccessible brain lesions.

Conclusions:

  • Laser interstitial thermal therapy is a viable, less invasive surgical alternative in neuro-oncology.
  • LITT demonstrates comparable efficacy and safety to established treatments.
  • Further prospective, randomized trials are needed to establish LITT as a primary treatment for brain metastases.