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Related Concept Videos

Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

542
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
542
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

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The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
202
Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

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Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
961
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

551
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
551
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

666
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
666
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

397
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
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Related Experiment Video

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A Mouse Model for Chronic Pancreatitis via Bile Duct TNBS Infusion
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Painless chronic pancreatitis.

Antonio Amodio1, Giulia De Marchi1, Nicolò de Pretis1

  • 1Gastroenterology B Unit, Department of Medicine, The Pancreas Institute, University and Hospital Trust of Verona, Policlinico GB Rossi, Piazzale L.A. Scuro, 10, 37134 Verona, Italy.

Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
|September 14, 2020
PubMed
Summary
This summary is machine-generated.

Painless chronic pancreatitis (CP) affects nearly 10% of patients and is often linked to exocrine pancreatic insufficiency (EPI). This condition rarely progresses to pain or severe complications in the short term.

Keywords:
Chronic pancreatitisDiagnosisPainlessPancreatic calcifications

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Area of Science:

  • Gastroenterology
  • Pancreatology

Background:

  • Painless chronic pancreatitis (CP) is an uncommon presentation of the disease.
  • Understanding its characteristics is crucial for accurate diagnosis and management.

Purpose of the Study:

  • To determine the prevalence of painless CP.
  • To characterize the clinical, imaging, and functional features of painless CP.

Main Methods:

  • Retrospective analysis of 781 patients diagnosed with CP between 2010 and 2016.
  • Selection of patients with CP and absence of pain, excluding autoimmune pancreatitis.
  • Analysis of clinical data, imaging, exocrine, and endocrine function.

Main Results:

  • 74 patients (9.5%) had painless CP, with a mean age at diagnosis of 60.8 years.
  • Common findings included pancreatic calcifications (95%), duct dilation (74%), and atrophy (53%).
  • Severe exocrine pancreatic insufficiency (EPI) affected 55% and diabetes 47% of patients. Few experienced new symptoms or complications during follow-up.

Conclusions:

  • Painless CP constitutes approximately 10% of cases in tertiary centers and is frequently associated with EPI.
  • The likelihood of developing pain or severe complications is low within a short follow-up period.