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Congenital Bleeding Disorders amid the COVID-19 pandemic: Open questions and recommendations

Majid Naderi1, Fatemeh Malek2, Ghasem Miri Aliabad3

  • 1Genetics of Non-Communicable Disease Research Center, Zahedan University of Medical Sciences, Zahedan, Iran,. majid_naderi2000@yahoo.com.

Acta Bio-Medica : Atenei Parmensis
|September 14, 2020
PubMed

Insights

Patients with congenital bleeding disorders (CBD) do not appear to have a higher risk of COVID-19 infection. Outpatient management strategies emphasize adherence to treatment and risk assessment for bleeding or thrombosis.

Area of Science:

  • Hematology
  • Infectious Diseases
  • Public Health

Background:

  • Congenital bleeding disorders (CBD) represent a group of inherited conditions affecting hemostasis.
  • The emergence of the COVID-19 pandemic raised concerns about its impact on vulnerable patient populations, including those with CBD.

Purpose of the Study:

  • To review current knowledge on congenital bleeding disorders (CBD) in the context of the COVID-19 pandemic.
  • To assess the risk of COVID-19 infection and its implications for patients with CBD.
  • To outline management strategies for patients with CBD during the pandemic.

Main Methods:

  • Literature review and synthesis of existing data and expert opinions.
  • Analysis of the prevalence of COVID-19 in individuals with CBD compared to the general population.
  • Evaluation of risk assessment for hemorrhage and thrombosis in this cohort.

Main Results:

  • Current data suggest that CBD is not associated with an increased risk of contracting COVID-19.
  • The prevalence of COVID-19 among patients with CBD appears similar to that in the general population.
  • In the absence of specific therapeutic guidelines, careful assessment of bleeding/thrombosis risk is crucial.

Conclusions:

  • Patients with CBD do not face a higher risk of COVID-19 infection.
  • Outpatient management should focus on treatment adherence, telemedicine, and clear communication regarding COVID-19.
  • Further research is needed to fully understand the impact of SARS-CoV-2 on CBD patients and to develop targeted preventive measures.

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