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Respiratory infections in allergic children: the preventive role of a multicomponent nutraceutical
Anna Maria Zicari1, Giovanan De Castro1, Giulia Brindisi1
1Pediatrics Department , Umberto I Hospital, Roma, Sapienza University , Roma, Italy. gio.cip@libero.it.
Insights
A multicomponent nutraceutical significantly reduced respiratory infections and antibiotic use in allergic children. This finding offers a promising strategy for managing allergic rhinoconjunctivitis and combating antibiotic resistance in pediatric care.
Area of Science:
- Pediatric Allergy and Immunology
- Infectious Disease Management
- Nutraceutical Research
Background:
- Allergic children frequently experience respiratory infections (RI), posing challenges for pediatricians.
- Antibiotic overuse in children with allergic rhinoconjunctivitis contributes to antimicrobial resistance.
- Modulating the immune system is a potential strategy for preventing RI in this population.
Purpose of the Study:
- To evaluate the efficacy of a multicomponent nutraceutical in reducing RI and antibiotic use.
- To compare outcomes in children with allergic rhinoconjunctivitis receiving a nutraceutical versus a control group.
Main Methods:
- A prospective study involving two groups of children with allergic rhinoconjunctivitis.
- The active group (AG) received a nutraceutical (Lertal®) before a 1-year observation period.
- The control group (CG) did not receive the nutraceutical.
- Primary outcomes measured were the number of RI and antibiotic courses.
Main Results:
- Children in the AG experienced a significantly lower number of RI compared to the CG (p=0.01).
- The AG also showed a significant reduction in antibiotic courses compared to the CG (p=0.002).
Conclusions:
- A course of the studied multicomponent nutraceutical can effectively reduce respiratory infections in children with allergic rhinoconjunctivitis.
- This intervention may decrease the need for antibiotic prescriptions, aiding in the fight against antibiotic resistance.
Abstract:
Allergic children with respiratory infections (RI) are a demanding challenge for the paediatrician. Antibiotic prescription represents a critical problem, mainly concerning the growing issue of resistance. To prevent RI would be therefore a goal in clinical practice. In this regard, modulation of immune system may have a critical role. The aim of the present study was to measure the number of respiratory infections and the use of antibiotics in two groups of children suffering from allergic rhinoconjunctivitis. The first group took a course of a nutraceutical (Lertal®) before the observation (active group, AG); a second one was considered as control (control group, CG). The children were visited at baseline and after 1 year. The number of RI and of antibiotic courses was the primary outcomes. Children in AG reported a significant reduced number of RI and of antibiotic course in comparison with CG (p=0.01 and 0.002 respectively). In conclusion, the current study showed that a course with a multicomponent nutraceutical could reduce the number of respiratory infections and consequently the use of antibiotics in children with allergic rhinoconjunctivitis.
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