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Related Experiment Videos

Esophageal motility disorders.

J B Nelson1, D O Castell

  • 1Department of Medicine, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina.

Disease-A-Month : DM
|June 1, 1988
PubMed
Summary
This summary is machine-generated.

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Esophageal motility disorders disrupt normal swallowing and can cause dysphagia and chest pain. Advances in diagnostics have improved understanding and management of conditions like achalasia and diffuse esophageal spasm (DES).

Area of Science:

  • Gastroenterology
  • Esophageal Physiology
  • Digestive Diseases

Background:

  • Esophageal motility disorders are complex disturbances affecting normal esophageal function.
  • These disorders are associated with symptoms like dysphagia, gastroesophageal reflux, and noncardiac chest pain.
  • Understanding normal esophageal anatomy and physiology is crucial for diagnosing motility derangements.

Purpose of the Study:

  • To provide a comprehensive overview of esophageal motility disorders.
  • To highlight the role of neuromuscular and hormonal influences on esophageal function.
  • To discuss the advancements in diagnostic tools and their impact on understanding these conditions.

Main Methods:

  • Review of current literature on esophageal motility.

Related Experiment Videos

  • Discussion of diagnostic modalities including barium radiography, scintigraphy, pH monitoring, and esophageal manometry.
  • Categorization of primary and secondary esophageal motility disorders.

    • Main Results:

    • Primary disorders include achalasia, diffuse esophageal spasm (DES), "nutcracker esophagus," hypertensive lower esophageal sphincter, and nonspecific esophageal motility dysfunction (NEMD).
    • Secondary disorders encompass conditions like scleroderma, diabetes mellitus, Chagas' disease, and neuromuscular disorders.
    • Motility disturbances can promote gastroesophageal reflux disease (GERD).

    Conclusions:

    • Improved diagnostic tools have enhanced the definition and understanding of esophageal motility disorders.
    • Treatment options range from surgical myotomy and dilatation to pharmacologic interventions.
    • A thorough grasp of esophageal function is essential for managing these complex conditions.