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QRS-T-angle in Patients with ST-Segment Elevation Myocardial Infarction (STEMI) - a Comparison with Cardiac Magnetic
B Zadeh1,2, J M Wambach1,2, M Lambers1,2
1Department of Cardiology and Angiology, Contilia Heart and Vascular Center, Elisabeth-Krankenhaus Essen, Essen, Germany.
Insights
The QRS-T angle on an electrocardiogram (EKG) is linked to greater myocardial damage in ST-segment myocardial infarction (STEMI) patients. A larger QRS-T angle indicates more extensive heart muscle damage, as confirmed by cardiovascular magnetic resonance imaging.
Area of Science:
- Cardiology
- Medical Imaging
- Electrocardiography
Background:
- The QRS-T angle on surface electrocardiograms (EKG) shows prognostic value in coronary artery disease.
- Cardiovascular magnetic resonance (CMR) with late gadolinium enhancement (LGE) provides detailed imaging of myocardial damage.
Purpose of the Study:
- To investigate the association between the QRS-T angle and the extent of myocardial damage assessed by LGE.
- To evaluate the relationship between QRS-T angle and infarct size in ST-segment myocardial infarction (STEMI) patients.
Main Methods:
- 169 STEMI patients underwent EKG for QRS-T angle calculation and CMR with LGE for infarct size assessment within the first week.
- Patients were categorized based on QRS-T angle: abnormal (≥ 90 degrees) versus normal (< 90 degrees).
Main Results:
- Patients with a QRS-T angle ≥ 90 degrees exhibited significantly larger infarct sizes (36.5±12.4 vs. 13.3±9.5; p<0.001).
- An abnormal QRS-T angle was associated with lower ejection fraction (42.9±12.1% vs. 50.6±10.6%; p<0.001).
Conclusions:
- The extent of myocardial damage, quantified by LGE, is significantly associated with a larger QRS-T angle.
- The QRS-T angle derived from surface EKG is a valuable indicator of myocardial damage extent in STEMI.
Abstract:
Background: The QRS-T angle from the surface EKG is a promising prognostic marker in patients with coronary artery disease. Cardiovascular magnetic resonance (CMR) imaging with late gadolinium enhancement (LGE) offers high resolution imaging of myocardial damage. We investigated the association of the QRS-T angle and the extent of myocardial damage as assessed by LGE in patients with acute ST-segment myocardial infarction (STEMI) Methods: 169 patients with STEMI obtained a standardized digital 12-lead EKG on admission for the calculation of the QRS-T angle and underwent CMR imaging for analysis of infarct size by LGE within the first week. Patients were divided into groups: (1) abnormal QRS-T angle ≥ 90 degree and (2) QRS-T angle < 90 degree. Results: Patients with a QRS-T angle of 90 degree or more had larger infarcts (36.5±12.4 vs. 13.3±9.5; p<0.001) and lower ejection fraction (42.9±12.1% vs. 50.6±10.6%; p<0.001). Conclusion: The extent of myocardial damage as measured by the gold standard LGE is associated with a larger QRS-T angle calculated from the surface EKG.
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