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Proximal-type epithelioid sarcoma in the maxillary sinus: an unusual presentation
Weijin Gao1, Jincai Xue2, Chunyue Ma3
1Department of Stomatology, The First Affiliated Hospital of Wenzhou Medical University Wenzhou, China.
International Journal of Clinical and Experimental Pathology
|September 14, 2020
Summary
Proximal-type epithelioid sarcoma (ES) is a rare aggressive cancer. This case report details the first instance of proximal-type ES in a maxillary sinus of a young female patient.
Area of Science:
- Oncology
- Pathology
- Surgical Oncology
Background:
- Epithelioid sarcoma (ES) is a rare soft tissue sarcoma.
- Proximal-type ES is a recently described aggressive variant.
- Limited data exists on head and neck ES.
Observation:
- A 16-year-old female presented with cheek swelling and pain.
- Radiographic and physical exams revealed a maxillary sinus malignancy with bone invasion.
- Pathological and immunohistochemical analysis confirmed proximal-type ES.
Findings:
- The patient underwent subtotal maxillectomy with wide margins.
- The patient experienced an uneventful three-year survival post-surgery.
- This is the first reported case of proximal-type ES in the maxillary sinus.
Implications:
- Highlights the potential for proximal-type ES in the head and neck.
- Emphasizes the need for increased awareness and diagnostic consideration.
- Suggests surgical resection as a viable treatment option for localized disease.

