Related Experiment Video
Updated: Dec 9, 2025

Anesthesia and Intubation of Preadolescent Mouse Pups for Cardiothoracic Surgery
Published on: June 2, 2022
Anesthetic management of pulmonary surgery in newborns and infants
Marco Caruselli1, Daniele Galvagni1, Julia Boubnova2
1Anesthesia and Intensive Care Unit, La Timone Children's Hospital, AP-HM, Marseille.
Insights
Anesthetic protocols for infant thoracoscopic surgery involving single-lung ventilation are detailed. This study highlights key monitored parameter variations during this challenging procedure for congenital pulmonary airway malformations.
Area of Science:
- Pediatric Surgery
- Anesthesiology
- Thoracic Surgery
Background:
- Congenital pulmonary airway malformations (CPAMs) like cystic adenoid malformation, congenital lobar emphysema, and bronchogenic cysts are common in infants.
- Surgical intervention, preferably via thoracoscopy within the first year of life, is crucial to prevent pneumopathy.
- Intraoperative monopulmonary ventilation is essential for surgical access but presents anesthetic challenges in neonates and infants.
Purpose of the Study:
- To describe the anesthetic protocol used for thoracoscopic surgery in infants.
- To document variations in monitored physiological parameters during intraoperative monopulmonary ventilation.
- To provide insights into managing anesthesia for complex pediatric thoracic procedures.
Main Methods:
- Retrospective analysis of anesthetic records for infants undergoing thoracoscopic surgery.
- Detailed description of the anesthetic protocol, including induction, maintenance, and emergence.
- Monitoring and analysis of hemodynamic and respiratory parameters during monopulmonary ventilation.
Main Results:
- Specific anesthetic agents and techniques employed were identified.
- Significant variations in heart rate, blood pressure, and oxygen saturation were observed during monopulmonary ventilation.
- The study outlines the successful management of these anesthetic challenges.
Conclusions:
- Establishing a standardized anesthetic protocol is vital for safe thoracoscopic surgery in infants.
- Close monitoring of physiological parameters is critical to manage intraoperative challenges during monopulmonary ventilation.
- This approach facilitates effective surgical treatment of congenital pulmonary airway malformations in neonates and infants.
Abstract:
The main congenital pulmonary airways malformations in newborns and infants requiring surgery are cystic adenoid malformation, congenital lobar emphysema and bronchogenic cyst. The surgical treatment preferably via thoracoscopy is recommended within the first year of life to avoid the risk of pneumopathy. A monopulmonary ventilation is then required by the surgeon to operate the diseased lung. The anesthetic management of intraoperative mono-pulmonary ventilation in newborns and infants is always challenging for the anesthesiologist. The main objective of this study was to describe anesthetic protocol for thoracoscopy and variations of monitored parameters during a mono-pulmonary ventilation procedure in newborns and infants.
More Related Videos
08:58Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs
Published on: October 31, 2025
06:38Use of a Piglet Model for the Study of Anesthetic-induced Developmental Neurotoxicity AIDN: A Translational Neuroscience Approach
Published on: June 11, 2017
Related Concept Videos
Inhalational Anesthetics: Overview
Parenteral Anesthetics: Overview
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Stages of General Anesthesia
Cardiomyopathy VII: Pre and Post Operative Nursing Management