Efficient simulation of a low-profile visualized intraluminal support device: a novel fast virtual stenting technique

Area of Science:

• Biomedical Engineering
• Medical Imaging
• Computational Fluid Dynamics

Background:

• The low-profile visualized intraluminal support (LVIS) stent is a key endovascular treatment for intracranial aneurysms.
• Optimizing LVIS stent treatment requires accurate evaluation of hemodynamic changes within the aneurysm.

Purpose of the Study:

• To develop and validate a fast virtual stenting (F-LVIS) technique for assessing hemodynamic changes associated with LVIS stent placement.
• To compare the reliability of F-LVIS against real LVIS (R-LVIS) in a patient-specific aneurysm model.

Main Methods:

• A patient-specific aneurysm model was created using a 3D printer for comparison.
• Real LVIS (R-LVIS) stenting was performed in the physical model.
• The fast virtual stenting (F-LVIS) technique was applied to the same aneurysm model.
• Computational fluid dynamics (CFD) analysis was conducted for both R-LVIS and F-LVIS models to compare hemodynamic parameters.

Main Results:

• Hemodynamic parameters, including velocity and wall shear stress (WSS), showed high similarity between R-LVIS and F-LVIS.
• Distribution and magnitude of velocities and WSS were consistently matched.
• While R-LVIS showed slightly faster streams, variation tendencies in velocity and WSS were similar, with no statistically significant differences.

Conclusions:

• The F-LVIS technique reliably simulates hemodynamic factors in intracranial aneurysms.
• F-LVIS is an efficient, practical, and effective tool for evaluating hemodynamic changes in aneurysm treatment planning.