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A Case Report on Dengue Encephalitis With Optic Neuropathy.
1Medicine, Dr. Ziauddin Hospital, Karachi, PAK.
Cureus
|September 14, 2020
Summary
Dengue fever, a Flavivirus infection, can cause severe neurological complications like encephalitis and optic neuropathy. Prompt diagnosis and high-dose steroid treatment led to a full recovery in a young male patient.
Area of Science:
- Neuroscience
- Infectious Diseases
- Ophthalmology
Background:
- Dengue virus (Flavivirus) is endemic in tropical/subtropical regions, causing a spectrum of illness.
- Dengue fever can manifest with diverse symptoms, affecting multiple organ systems.
- Dengue virus serotypes DENV-2 and DENV-3 are frequently linked to neurological complications.
Observation:
- A 19-year-old male presented with encephalitis and optic neuropathy following dengue fever diagnosis.
- Diagnostic tools included brain MRI, electroencephalogram, fundoscopy, and visual evoked potential testing.
- The patient exhibited atypical dengue symptoms, indicating multi-systemic involvement.
Findings:
- Brain MRI, EEG, fundoscopy, and VEP confirmed encephalitis and optic neuropathy.
- High-dose intravenous steroid therapy was administered in pulses.
- The patient experienced complete visual and neurological recovery after treatment.
Implications:
- Dengue fever can present with unusual neurological manifestations, requiring clinical awareness.
- Early diagnosis of dengue-related neurological complications is crucial.
- Timely and effective treatment, such as pulsed steroid therapy, can significantly improve patient outcomes and reduce long-term morbidity.
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