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Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
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Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
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Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
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Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
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Chronic Bowel Disorders: Introduction01:17

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
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Updated: Dec 9, 2025

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Extraintestinal Clostridioides difficile infection.

Zhao Hai1, Lei Peng Zhen2, Ma Juan1

  • 1Clinical Laboratory Department of Shaanxi Provincial People's Hospital, Xi'an City, Shaanxi Province, China.

Idcases
|September 14, 2020
PubMed
Summary
This summary is machine-generated.

Extraintestinal Clostridioides (Clostridium) difficile infection (CDI) is rare. This case report details a non-027 strain causing extraintestinal CDI post-surgery, highlighting the importance of considering CDI beyond diarrhea.

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Surgical Infections
Keywords:
Clostridioides (clostridium) tissue infection infectious control

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Background:

  • Clostridioides (Clostridium) difficile is a leading cause of antibiotic-associated diarrhea in healthcare settings.
  • Extraintestinal manifestations of Clostridioides (Clostridium) difficile infection (CDI), such as bacteremia and tissue infections, are exceptionally uncommon.
  • The prevalence of specific hypervirulent strains like PCR ribotype 027 is a significant factor in CDI epidemiology.