Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum to "Multifunctional piezoelectric surfaces enhanced with layer-by-layer coating for improved osseointegration and antibacterial performance" [Colloids Surf. B: Biointerfaces 243 (2024) 114123].

Colloids and surfaces. B, Biointerfaces·2026
Same author

Remote control of protein deposition on magnetoactive composites.

Colloids and surfaces. B, Biointerfaces·2026
Same author

Ovary-Derived Signals Align Protein Appetite with Oogenesis.

bioRxiv : the preprint server for biology·2026
Same author

Vibration or Stretch? Distinct Mechanoelectrical Signatures Govern Osteogenic Programming in PVDF.

ACS applied materials & interfaces·2026
Same author

Optimizing Biodegradable Poly(D,L-lactide) Scaffolds Reinforced with Graphene Oxide for Bone Tissue Regeneration.

Biomimetics (Basel, Switzerland)·2025
Same author

Connectomics Reveals a Feed-Forward Swallowing Circuit Driving Protein Appetite.

bioRxiv : the preprint server for biology·2025
Same journal

Cyclic Stiffness Modulation of Cell-Laden Protein-Polymer Hydrogels in Response to User-Specified Stimuli including Light.

Advanced biosystems·2021
Same journal

Biomimetic microgels with controllable deformability improve healing outcomes.

Advanced biosystems·2021
Same journal

Single Extracellular Vesicle Protein Analysis Using Immuno-Droplet Digital Polymerase Chain Reaction Amplification.

Advanced biosystems·2020
Same journal

The Magical World of Circulating Vesicles.

Advanced biosystems·2020
Same journal

On the Assembly of Microreactors with Parallel Enzymatic Pathways.

Advanced biosystems·2020
Same journal

A Dual Role of Type I Interferons in Antitumor Immunity.

Advanced biosystems·2020
See all related articles

Related Experiment Video

Updated: Dec 9, 2025

Design of a Biaxial Mechanical Loading Bioreactor for Tissue Engineering
08:04

Design of a Biaxial Mechanical Loading Bioreactor for Tissue Engineering

Published on: April 25, 2013

14.8K

Physically Active Bioreactors for Tissue Engineering Applications.

N Castro1, S Ribeiro2,3, M M Fernandes2,4

  • 1BCMaterials, Basque Centre for Materials, Applications and Nanostructures, University of the Basque Country UPV/EHU Science Park, Leioa, E-48940, Spain.

Advanced Biosystems
|September 14, 2020
PubMed
Summary
This summary is machine-generated.

Tissue engineering utilizes smart materials and bioreactors to create biomimetic microenvironments for cell growth. Microfluidic bioreactors show promise for advanced tissue engineering strategies.

Keywords:
bioreactorscell microenvironmentmicrofluidicphysical stimulismart materials

More Related Videos

A Multi-Cue Bioreactor to Evaluate the Inflammatory and Regenerative Capacity of Biomaterials under Flow and Stretch
07:51

A Multi-Cue Bioreactor to Evaluate the Inflammatory and Regenerative Capacity of Biomaterials under Flow and Stretch

Published on: December 10, 2020

6.0K
Hollow Fiber Bioreactors for In Vivo-like Mammalian Tissue Culture
08:28

Hollow Fiber Bioreactors for In Vivo-like Mammalian Tissue Culture

Published on: May 26, 2016

16.8K

Related Experiment Videos

Last Updated: Dec 9, 2025

Design of a Biaxial Mechanical Loading Bioreactor for Tissue Engineering
08:04

Design of a Biaxial Mechanical Loading Bioreactor for Tissue Engineering

Published on: April 25, 2013

14.8K
A Multi-Cue Bioreactor to Evaluate the Inflammatory and Regenerative Capacity of Biomaterials under Flow and Stretch
07:51

A Multi-Cue Bioreactor to Evaluate the Inflammatory and Regenerative Capacity of Biomaterials under Flow and Stretch

Published on: December 10, 2020

6.0K
Hollow Fiber Bioreactors for In Vivo-like Mammalian Tissue Culture
08:28

Hollow Fiber Bioreactors for In Vivo-like Mammalian Tissue Culture

Published on: May 26, 2016

16.8K

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Cell Biology

Background:

  • Tissue engineering (TE) aims to regenerate tissues by mimicking the natural microenvironment.
  • The extracellular matrix provides structural support and biochemical/biophysical cues crucial for cell behavior.
  • 3D microenvironment characteristics significantly influence in vivo cell responses.

Purpose of the Study:

  • To review microenvironments, smart materials, and bioreactor technologies in tissue engineering.
  • To highlight the role of biomimetic stimuli in controlling cell behavior.
  • To assess the potential of microfluidic bioreactors for TE applications.

Main Methods:

  • Comprehensive literature review of smart materials and bioreactor technologies for TE.
  • Analysis of how different microenvironments influence cell and tissue development.
  • Evaluation of bioreactor systems providing biochemical and biophysical cues.

Main Results:

  • Smart materials enable precise control over cellular behavior through tailored stimuli.
  • Bioreactors are essential for creating in vitro biomimetic microenvironments.
  • Microfluidic bioreactors are emerging as a powerful tool for TE.

Conclusions:

  • Advanced materials and bioreactor technologies are critical for successful tissue engineering.
  • Biomimetic microenvironments are key to achieving desired cell responses.
  • Microfluidic bioreactors offer significant potential for future TE strategies.