Related Experiment Video
Updated: Dec 9, 2025

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
Published on: September 26, 2019
[Stiff skin syndrome in a pediatric patient: a therapeutic challenge. Clinical case]
Montserrat Colombarolli1, Alejandro Olivera2, Mariángeles Domínguez2
1Servicio de Dermatología, Hospital Universitario Austral, Universidad Austral, Pilar, provincia de Buenos Aires, Argentina. mcolomba@cas.austral.edu.ar.
Abstract:
Stiff skin syndrome is a chronic, rare sclerosing disorder that occurs in childhood, characterized by progressive induration of the skin that can cause thoracic restrictions and respiratory distress, limitations in joint mobility and gait difficulties, with significant deterioration of the quality of life. Because their therapeutic options are scarce and ineffective it is essential to start an early physical therapy to prevent these complications and to continue studying this condition to be able to offer patients more and better treatments. We present the case of a 9-year-old patient with indurated skin syndrome and its therapeutic challenge.
Related Concept Videos
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Changes in Skin Color: Clinical Perspectives
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Clinical Applications of Epidermal Stem Cells
Renewal of Skin Epidermal Stem Cells
Nephrotic Syndrome II : Assessment and Medical Management
Cystic Fibrosis: Management
Sinus disease and chronic...

