Diagnostic approaches in COVID-19: clinical updates

Area of Science:

• * Medical Diagnostics
• * Infectious Disease Management

Background:

• * The COVID-19 pandemic presents ongoing challenges with unclear prognosis.
• * Accurate diagnostic tools are crucial for infection control and disease monitoring.

Purpose of the Study:

• * To conduct a narrative and critical review of technology-based diagnostic strategies for COVID-19.
• * To provide an overview of FDA-authorized diagnostic kits and point-of-care devices.

Main Methods:

• * Review of molecular approaches (e.g., real-time RT-PCR).
• * Analysis of serological testing (e.g., ELISA).
• * Evaluation of radiology (CT, X-ray) and cell culture methods.
• * Inclusion of FDA emergency use authorized devices.

Main Results:

• * Detailed discussion of various diagnostic technologies for COVID-19.
• * Overview of FDA-authorized immunodiagnostic and molecular diagnostic kits.
• * Consideration of point-of-care (POC) devices for timely testing.

Conclusions:

• * Information is vital for healthcare professionals to conduct accurate diagnostic tests.
• * Addressing limitations of available methods can lead to better clinical strategies.
• * The review synthesizes information from WHO, CDC, and FDA guidelines.