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A Mobile Gaming Intervention for Persons on Pre-Exposure Prophylaxis: Protocol for Intervention Development and
Laura Whiteley1, Elizabeth Olsen1, Leandro Mena2
1Department of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University, Providence, RI, United States.
JMIR Research Protocols
|September 14, 2020
Summary
This study developed an app/gaming intervention to improve pre-exposure prophylaxis (PrEP) adherence and HIV prevention behaviors in young men who have sex with men (MSM). The engaging intervention aims to increase motivation and knowledge, potentially reducing HIV transmission.
Area of Science:
- Digital health interventions
- HIV prevention strategies
- Behavioral science in public health
Background:
- Young minority men who have sex with men (MSM) face the highest HIV infection rates in the US.
- Pre-exposure prophylaxis (PrEP) is effective but requires high adherence for maximum benefit.
- Suboptimal adherence to PrEP compromises its safety and effectiveness.
Purpose of the Study:
- To develop and test an engaging app/gaming intervention for young MSM.
- To improve adherence to PrEP and enhance HIV prevention knowledge, skills, and behaviors.
- To combine a digital intervention with PrEP to maximize positive impact.
Main Methods:
- Qualitative interviews with young MSM (n=20) informed intervention development.
- A randomized controlled trial (RCT) tested the app/gaming intervention's preliminary efficacy.
- Participants (n=60) were recruited from HIV/STI testing clinics.
Main Results:
- Study activities commenced in June 2015 and are ongoing.
- Institutional review board approval was obtained in February 2015.
- Preliminary efficacy testing of the gaming intervention is underway.
Conclusions:
- The app/gaming intervention aims to boost PrEP adherence and HIV preventative behaviors in young MSM.
- Engaging young MSM can improve motivation and adherence, potentially decreasing HIV seroconversion.
- Interventions must be enjoyable, engaging, and easily integrated into clinical settings.
