Related Experiment Video
Updated: Dec 9, 2025

Live Imaging of Antifungal Activity by Human Primary Neutrophils and Monocytes in Response to A. fumigatus
Published on: April 19, 2017
Ocular Phaeohyphomycosis Caused by Veronaea botryose: A Novel Fungal Infection in Human Beings
Samaneh Davoudi1, Nishi Shah, Gibran Khurshid
1Department of Ophthalmology, University of Florida College of Medicine, Gainesville, FL.
Purpose:
To describe an aggressive, refractory case of Veronaea botryosa-associated mycokeratitis progressing to endophthalmitis.
Methods:
Observational case report and review of relevant literature.
Results:
An 80-year-old man with a history of lung cancer and diabetes mellitus type 2 presented as an emergent referral to the corneal service with a corneal ulcer and associated endothelial plaque that responded initially to topical steroid and antiviral therapy but subsequently progressed to fungal endophthalmitis. The patient underwent an emergent penetrating keratoplasty and pars plana vitrectomy. Despite multiple negative Grocott methenamine silver smears, gram stains, eye cultures (aerobic, anaerobic, and fungal), and inconclusive confocal microscopy, the host corneal tissue pathology revealed melanin-containing fungi (phaeohyphomycosis). Further speciation of the pathology specimen revealed mold and phenotypic characterization and DNA sequencing confirmed V. botryose.
Conclusions:
Veronaea botryose is a rare fungal infection with previously reported human cutaneous, subcutaneous, and submucosal infections. This is the first documented case of phaeohyphomycosis caused by V. botryosa infection in human ocular tissue.
More Related Videos
Related Concept Videos
Fungal Group Zygomycota
Fungal Phylum Microsporidia
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Fungal Phylum Basidiomycota
Fungal Phylum Ascomycota
Diversity of Protists II

