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Updated: Dec 9, 2025

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
Bronchus compression relieved by patent ductus arteriosus stenting.
Wagih M Zayed1, Krishna Bhandari1, Peter W Guyon1
1Division of Pediatric Cardiology, Rady Children's Hospital and UC San Diego School of Medicine, San Diego, California.
Patent ductus arteriosus (PDA) stenting can relieve bronchial compression in infants. This procedure improved airway compression in patients with ductal-dependent pulmonary blood flow, showing PDA stenting is a viable option.
Area of Science:
- Pediatric Cardiology
- Interventional Cardiology
- Thoracic Surgery
Background:
- Patent ductus arteriosus (PDA) stenting is an emerging alternative to surgical shunts for ductal-dependent pulmonary blood flow in infants.
- Anatomical proximity of PDA can lead to ipsilateral bronchial compression.
- This case series investigates PDA stenting in patients with pre-existing bronchial compression.
Purpose of the Study:
- To evaluate the efficacy of PDA stenting in infants with bronchial compression.
- To assess the impact of PDA stenting on relieving airway compression.
- To identify factors influencing bronchial compression related to PDA characteristics.
Main Methods:
- Retrospective review of four infants with ductal-dependent pulmonary blood flow and bronchial compression who underwent PDA stenting.
- Analysis of pre- and post-procedure cross-sectional chest imaging.
- Assessment of PDA size, tortuosity, and anatomical relationship with the bronchus.
Main Results:
- Post-procedure imaging in three patients showed complete relief of bronchial compression.
- Successful PDA stenting resulted in a smaller, straighter PDA with lateralization away from the bronchus.
- No patients developed symptoms of bronchial compression after the procedure.
Conclusions:
- Pre-existing bronchial compression does not contraindicate PDA stenting.
- PDA stenting effectively improves pre-existing bronchial compression, likely due to PDA shrinkage, straightening, and lateralization.
- Further research is warranted to validate these findings.
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