Related Experiment Video
Updated: Jul 15, 2026

05:12
Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
Published on: May 12, 2023
4.4K
Infected Recurrent Thyroglossal Duct Cyst: A Case Report
Jennifer Foti1, Felipe Grimaldo1
1Naval Medical Center San Diego, Department of Emergency Medicine, San Diego, California.
Clinical Practice and Cases in Emergency Medicine
|September 14, 2020
Summary
Recurrent thyroglossal duct cyst (TGDC) infection can occur even after childhood surgery. This case highlights the importance of considering infected recurrent TGDC in adults with neck masses and fever.
Area of Science:
- Otolaryngology
- Pediatric Surgery
- Head and Neck Surgery
Background:
- Thyroglossal duct cysts (TGDC) are congenital neck malformations.
- Surgical excision is common due to infection risk and rare malignancy potential.
Purpose of the Study:
- To report a case of recurrent thyroglossal duct cyst (TGDC) with infection in an adult.
- To emphasize diagnostic considerations following prior surgical intervention.
Main Methods:
- Case report of an adult patient with a tender neck mass and fever.
- Review of patient history including childhood TGDC excision.
- Computed tomography (CT) imaging to evaluate the recurrent TGDC and infection.
Main Results:
- The patient presented with symptoms of an infected recurrent TGDC.
- CT imaging confirmed the presence of a recurrent TGDC complicated by acute infection.
Conclusions:
- Recurrence of thyroglossal duct cysts (TGDC) after surgical removal is possible.
- Infected recurrent TGDC should be considered in the differential diagnosis for adults with neck masses, especially after prior surgery.
Related Concept Videos
The Thyroid Gland
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Hyperthyroidism II: Pathophysiology
Hyperthyroidism is a hypermetabolic state caused by elevated levels of thyroid hormones, triiodothyronine (T3) and thyroxine (T4). It results from dysregulation at the thyroid, pituitary, or immune system level and affects multiple organ systems.PathophysiologyThe most common cause of hyperthyroidism is Graves’ disease, an autoimmune disorder in which antibodies, specifically thyroid-stimulating antibodies (TSAb), a subtype of TSH receptor antibodies (TRAb), bind to and activate TSH receptors...
Graves' Disease I: Introduction
Graves' disease is an autoimmune disorder that causes hyperthyroidism, or overactivity of the thyroid gland. It results from autoantibodies called thyroid-stimulating immunoglobulins (TSIs), which bind to thyroid-stimulating hormone (TSH) receptors, leading to overstimulation of hormone production and a hypermetabolic state.EtiologyAlthough considered idiopathic, Graves’ disease has well-established contributing factors. There is a strong genetic component, with increased prevalence in...
Graves Disease II: Pathophysiology
Graves’ disease is an autoimmune disorder characterized by the production of thyroid-stimulating immunoglobulins (TSI) that activate TSH receptors, leading to excessive synthesis and release of thyroid hormones (T3 and T4) and resulting in hyperthyroidism.Among all causes of hyperthyroidism, Graves’ disease is the most common and can happen at any age, though it is more frequent in women. It produces a hypermetabolic state with features such as weight loss, tachycardia, tremor, and heat...
Goiter
Goiter refers to an abnormal enlargement of the thyroid gland that may appear as a diffuse goiter (uniform enlargement) or nodular (single or multiple nodules). Functionally, it is classified as nontoxic (normal/low hormone levels) or toxic (excess hormone production).PathophysiologyDiffuse thyroid enlargement typically results from prolonged stimulation by thyroid-stimulating hormone (TSH) or TSH-like agents, commonly seen in hypothyroidism or iodine deficiency. In contrast, in hyperthyroid...

