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Updated: Dec 9, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
48-year-old with Coronavirus Disease 2019
Holly Gil1, Ryan M Finn2, Neha P Raukar2
1Brown University, Department of Radiology, Providence, Rhode Island.
Early coronavirus disease 2019 (COVID-19) may present as a common upper respiratory infection. Chest imaging findings suggestive of COVID-19 can evolve, necessitating careful evaluation of worsening symptoms.
Area of Science:
- Pulmonology
- Infectious Diseases
- Radiology
Background:
- Coronavirus disease 2019 (COVID-19) is a novel infectious disease.
- Initial symptoms can mimic common upper respiratory infections.
- Radiographic findings may not be immediately apparent.
Purpose of the Study:
- To highlight the initial presentation of COVID-19.
- To emphasize the importance of serial imaging in suspected cases.
- To discuss the spectrum of chest imaging findings in COVID-19.
Main Methods:
- Case report of a 48-year-old male with worsening respiratory symptoms.
- Review of initial urgent care presentation and subsequent emergency department visit.
- Analysis of chest radiograph and computed tomography findings.
Main Results:
- Initial presentation was consistent with an upper respiratory infection.
- Chest radiograph at initial presentation was negative.
- Worsening shortness of breath prompted further evaluation and imaging.
Conclusions:
- COVID-19 can present insidiously with non-specific symptoms.
- Chest imaging, including CT, plays a crucial role in diagnosing COVID-19.
- Radiographic findings may evolve over time in COVID-19 patients.
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