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Bilateral Foot Skin Eruption in a Hepatitis C Patient
1Virginia Commonwealth University Health Systems, Department of Emergency Medicine, Richmond, Virginia.
Clinical Practice and Cases in Emergency Medicine
|September 14, 2020
Summary
Necrolytic acral erythema (NAE) is a rare skin condition linked to hepatitis C. This case highlights NAE as an extra-hepatic manifestation, showing symptom improvement with targeted treatment.
Area of Science:
- Dermatology
- Hepatology
- Internal Medicine
Background:
- Hepatitis C virus (HCV) infection can lead to various extra-hepatic manifestations.
- Necrolytic acral erythema (NAE) is a rare dermatological condition associated with HCV.
- NAE typically presents as lesions on the feet.
Purpose of the Study:
- To report a case of Necrolytic acral erythema (NAE) in a patient with a history of hepatitis C virus.
- To describe the clinical presentation, diagnosis, and management of NAE.
- To emphasize NAE as a potential extra-hepatic manifestation of HCV.
Main Methods:
- A 58-year-old female with a history of HCV presented with a year-long bilateral foot eruption.
- Skin biopsy confirmed the diagnosis of Necrolytic acral erythema (NAE).
- Treatment included clobetasol ointment, zinc supplementation, and mupirocin.
Main Results:
- The patient's skin eruption showed significant improvement following the prescribed treatment.
- The diagnosis of NAE was confirmed via skin biopsy.
- The clinical presentation was consistent with previously described cases of NAE.
Conclusions:
- Necrolytic acral erythema (NAE) is a rare extra-hepatic manifestation of hepatitis C.
- NAE typically presents as sharply demarcated, lichenified plaques on the dorsal foot.
- This case underscores the importance of considering NAE in HCV patients with characteristic foot lesions.
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