Related Experiment Video

Updated: Dec 9, 2025

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
06:45

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis

Published on: February 10, 2023

15.3K

Point-of-care Ultrasound in the Diagnosis of Calciphylaxis

Natasha Tobarran1, Mark Collin1

  • 1Wellspan York Hospital, Department of Emergency Medicine, York, Pennsylvania.

Clinical Practice and Cases in Emergency Medicine
|September 14, 2020
PubMed

Insights

Calciphylaxis is a rare, lethal vascular disease causing necrotic skin ulcers, often seen in end-stage renal disease patients. Emergency physicians must consider calciphylaxis in their differential diagnosis due to its high mortality rate.

Area of Science:

  • Vascular Medicine
  • Nephrology
  • Dermatology

Background:

  • Calciphylaxis is a rare and often fatal condition characterized by vascular calcification and skin necrosis.
  • Patients with end-stage renal disease (ESRD) are at increased risk.
  • Early recognition is crucial for patient outcomes.

Purpose of the Study:

  • To present a case of calciphylaxis in a patient with end-stage renal disease.
  • To highlight the diagnostic challenges and clinical presentation of this rare disease.
  • To emphasize the importance of considering calciphylaxis in the differential diagnosis for emergency physicians.

Main Methods:

  • Case report of a 63-year-old male with ESRD.
  • Clinical presentation of painful, lower-extremity necrotic ulcerations.
  • Diagnostic workup including ultrasound, computed tomography, and skin biopsy.

Main Results:

  • Imaging revealed suspicious calcium deposits.
  • Biopsy confirmed the diagnosis of calciphylaxis.
  • The patient presented with severe necrotic ulcerations.

Conclusions:

  • Calciphylaxis is a critical diagnosis that emergency physicians must consider.
  • The high mortality rate associated with calciphylaxis necessitates prompt recognition and management.
  • This case underscores the importance of a high index of suspicion in patients with risk factors.
Abstract

More Related Videos

Treatment Protocol for Rotator Cuff Calcific Tendinitis Using a Single-Crystal Piezoelectric Focused Shock Wave Source05:17

Treatment Protocol for Rotator Cuff Calcific Tendinitis Using a Single-Crystal Piezoelectric Focused Shock Wave Source

Published on: December 23, 2022

3.1K
Author Spotlight: Advancing Cardiovascular Imaging - Introducing the Spatially Weighted Calcium Score for Early Disease Detection06:57

Author Spotlight: Advancing Cardiovascular Imaging - Introducing the Spatially Weighted Calcium Score for Early Disease Detection

Published on: September 22, 2023

1.3K

Related Concept Videos

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
255
Ultrasonography01:17

Ultrasonography

Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called...
7.1K
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
216