Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bone densitometry in infants.

H S Barden1, R B Mazess

  • 1Lunar Radiation Corporation, Madison, Wisconsin, 53713-2698.

The Journal of Pediatrics
|July 1, 1988
PubMed
Summary

New X-ray absorptiometry methods offer rapid and precise bone density measurements in infants, overcoming limitations of older techniques like single-photon absorptiometry (SPA) and dual-photon absorptiometry (DPA).

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Femur strength index predicts hip fracture independent of bone density and hip axis length.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2006
Same author

A review of intravenous versus oral vitamin D hormone therapy in hemodialysis patients.

Clinical nephrology·2003
Same author

The bone mineral density of the right and left femur in a large group of white women.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2001
Same author

Peak bone mass, reference values, and T-scores.

Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry·2001
Same author

PTH treatment: safety studies needed.

Calcified tissue international·2001
Same author

Efficacy and side effects of intermittent intravenous and oral doxercalciferol (1alpha-hydroxyvitamin D(2)) in dialysis patients with secondary hyperparathyroidism: a sequential comparison.

American journal of kidney diseases : the official journal of the National Kidney Foundation·2001

Area of Science:

  • Pediatric Bone Health
  • Medical Imaging Technology
  • Neonatal Physiology

Background:

  • Noninvasive bone mineral mass and density measurement is crucial for pediatric health assessment.
  • Existing methods like dual-photon absorptiometry (DPA) and single-photon absorptiometry (SPA) have limitations in infant applications.
  • SPA, while used in infants, faces precision challenges with small bones like the radius.

Purpose of the Study:

  • To review and compare noninvasive bone densitometry techniques for infant assessment.
  • To highlight the limitations of current methods and introduce advancements in the field.
  • To evaluate the suitability of emerging technologies for neonatal bone mineral measurement.

Main Methods:

  • Review of absorptiometric procedures including single-photon absorptiometry (SPA), dual-photon absorptiometry (DPA), and quantitative computed tomography.
  • Discussion of modifications and applications of SPA and DPA in pediatric and neonatal populations.
  • Introduction of new dual-energy x-ray absorptiometry (DXA) methods for neonatal bone assessment.

Main Results:

  • SPA shows typical precision of ~5% in newborns for the radius but struggles with older linear scanners on the humerus (5-10% error).
  • DPA, while adaptable for small animals, is too time-consuming (20 min) for infants.
  • New dual-energy x-ray absorptiometry (DXA) enables rapid (1 min), precise (1%) measurements in neonates, assessing both axial and peripheral skeletons without soft tissue bolus.

Conclusions:

  • Traditional SPA and DPA methods present significant challenges for precise and efficient neonatal bone density assessment.
  • Emerging dual-energy x-ray absorptiometry (DXA) offers a breakthrough for rapid, accurate, and comprehensive skeletal evaluation in neonates.
  • Advancements in imaging technology are vital for improving the understanding and management of infant bone health.

Related Experiment Videos