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Related Experiment Videos

Innervation of the microcirculation.

B P Fleming1

  • 1Department of Physiology and Biophysics, University of Kentucky, College of Medicine, Lexington 40536.

Journal of Reconstructive Microsurgery
|April 1, 1988
PubMed
Summary
This summary is machine-generated.

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Sympathetic adrenergic nerves regulate peripheral circulation by altering nerve discharge to blood vessels. Understanding their structure and function is crucial for microsurgery success.

Area of Science:

  • Physiology
  • Neuroscience
  • Vascular Biology

Background:

  • Peripheral circulation is regulated by neurogenic control via nerve discharge to the vascular network.
  • Postganglionic sympathetic adrenergic nerves are the primary efferent pathway for neural control of circulation.
  • Microvascular response to neural input is influenced by innervation patterns.

Purpose of the Study:

  • To review the structure and function of adrenergic nerves.
  • To highlight aspects relevant to microsurgery.
  • To discuss the neurogenic control of peripheral circulation.

Main Methods:

  • Literature review focusing on adrenergic nerve function and microcirculation.
  • Analysis of the trophic influence of adrenergic nerves on vascular smooth muscle.

Related Experiment Videos

  • Examination of changes following surgical denervation and reinnervation.

    • Main Results:

    • Adrenergic nerves influence both the contractile state and trophic state of vascular smooth muscle.
    • Surgical denervation leads to degeneration and subsequent reinnervation of adrenergic nerve terminals.
    • A period of functional and morphologic changes in smooth muscle occurs post-denervation.

    Conclusions:

    • Adrenergic nerve structure and function are critical for effective neurogenic control of circulation.
    • Knowledge of these neural elements is vital for successful microsurgical interventions.
    • The trophic role of adrenergic nerves in vascular smooth muscle is significant.