The Effects of Allogeneic Blood Transfusion in Hepatic Resection

Area of Science:

• Hepatobiliary Surgery
• Transfusion Medicine
• Surgical Oncology

Background:

• Hepatectomy carries a high risk of perioperative bleeding.
• The impact of allogeneic blood transfusion on outcomes after hepatectomy requires investigation.

Purpose of the Study:

• To investigate the postoperative effects of allogeneic blood transfusion in patients undergoing hepatectomy for hepatocellular carcinoma.

Main Methods:

• Retrospective review of 385 patients who underwent hepatic resection.
• Propensity score matching to analyze the association of allogeneic blood transfusion with surgical outcomes and remnant liver regeneration.

Main Results:

• Allogeneic transfusion was associated with significantly higher rates of postoperative complications, liver failure, and ascites.
• Patients without transfusion showed more favorable liver function tests in the early postoperative period.
• No significant difference was observed in remnant liver regeneration or long-term survival between groups.

Conclusions:

• Allogeneic transfusion impacts early remnant liver function but not regeneration volume.
• Transfusion leads to poorer short-term outcomes but does not affect long-term prognosis after hepatectomy.